In accordance with the provisions of Act 12 of 2003, the Institute was brought under the supervision of the Federal Ministry of Science and Technology (FMST) in the year 2003. The first Council was inaugurated on the 27th of May, 2004 by the Honourable Minister of Science and Technology, Professor Turner T. Isoun. The 4^th and Immediate past Council was inaugurated in August 2018, by the Honourable Minister of Science and Technology, Dr Ogbonnaya Onu. The Governing Council consists of:

• the President of the Institute, as Chairman.
• the Vice President of the Institute as Vice Chairman.
• a representative of the Federal Ministry of Education (FME).
• a representative of the Federal Ministry of Science Technology and Innovation (FMSTI).
• a representative of the Federal Ministry of Finance (FMF).
• one person representing Public Interest.
• twelve members of the Institute are nominated by the Association of Science Laboratory Technologists of Nigeria (ASLTON); with two persons representing each of the six geo-political zones of the Federation in rotation for a term of three years.
• The DG/Registrar/CEO as Secretary.

The 5^th Governing Council of the Institute was inaugurated on the 14^th October 2021 by the Honourable Minister of State, Federal Minsitry of Science, Technology and Innovation at Abuja. Council Members are:

1. Elder Olu-Ajayi Oluranti Michael, FISLT                                Chairman
2. Mr. Gberindyer James Saa-Aondo, FISLT                                Vice Chairman
3. Mr. Chakyin Yusufu Gongwang, FISLT                                     Member
4. Mr. Kaigama Kaka Mallam, FISLT                                            Member
5. Alhaji Abubakare Adamu, FISLT                                               Member
6. Alhaji Yusuff Akeem Adebayo, FISLT                                       Member
7. Mr. Ikegwu Alphonsus Ikechukwu, FISLT                                 Member
8. Mr. Eze Emmanuel Ikechukwu, FISLT                                      Member
9.  Barr. Etuk Sunday Edet, FISLT                                                 Member
10. Dr. Alagoa Comfort Seki, FISLT                                                Member
11. Hon. Ishaq Ahmed Kana                                                             Member (Rep Public Interest)
12. Mr. Kehinde Osinaike                                                                 Member (Rep FME)
13. Alhaji Umar Shaibu A.                                                                Member (Rep FMSTI)
14. Yemi H. Gbadegesin – DG/Registrar/CEO                                 Secretary to the Council